In 2015 and 2016, Casey Muratori ran HandmadeCon, inviting many amazing programmers to come talk about what they do. You probably already know that Casey is a fantastic interviewer, and the talks are loaded with amazing insights.
Handmade Seattle, the spiritual successor to HandmadeCon, was started in 2019 by Abner Coimbre, the founder of Handmade Network. From the start, Handmade Seattle has been an independent conference, free from corporate sponsorships. The conferences are hybrid online/physical, so you can participate no matter where in the world you live.
Tickets can be purchased at the conference website.